The problems and limitations of the control of fungal diseases through the use of fungicides make the biological control of phytopathogenic fungi present as an alternative control method in the production of tomatoes (Lycopersicon esculentum M.) in greenhouse, which is limited by the incidence of oomycete Phytophthora capsici, being one of the most destructive diseases worldwide. The objective of this study was to evaluate the effect of four bio‑fungicides based on native strains of the genus Trichoderma against P. capsici, in the tomato production, called in the region "jitomate" variety Ramses, in greenhouse conditions in bed system. The bio‑fungicide based on T. harzianum presented the best average results with a survival of 76.4% and an average yield of 27% greater than the control group. All treatments with bioprepared had higher plant height and final biomass than the control group. Thus, the control treatment showed a 54% mortality, with an average yield of 11% lower than that of the biopreparates with native strains of Trichoderma spp. and greater than the inoculated treatment with P. capsici, which presented the highest incidence "disease" (40%), the lowest survival (26.3%) and a 64% decrease in fruit yield compared to the control.